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S2054

Sigma-Aldrich

Sodium gluconate

meets USP testing specifications

Synonym(s):

D-Gluconic acid sodium salt, 2,3,4,5,6-Pentahydroxycaproic acid sodium salt, D-Gluconate sodium salt, Sodium D-gluconate

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About This Item

Empirical Formula (Hill Notation):
C6H11NaO7
CAS Number:
527-07-1
Molecular Weight:
218.14
Beilstein/REAXYS Number:
3919651
EC Number:
208-407-7
MDL number:
MFCD00064210
UNSPSC Code:
12352201
PubChem Substance ID:
24899510
NACRES:
NA.21

biological source

microbial

Quality Level

200

agency

USP/NF
meets USP testing specifications

form

solid

color

beige

useful pH range

6.5 - 7.5

mp

170-175  °C

solubility

590 g/L at 25 °C

application(s)

pharmaceutical (small molecule)

storage temp.

room temp

SMILES string

[Na+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H12O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

UPMFZISCCZSDND-JJKGCWMISA-M

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Application

Sodium gluconate has been used as a component of recording buffer used in two-electrode voltage-clamp (TEVC) recording in Xenopus laevis oocytes. It has also been used as a control for sodium.

Biochem/physiol Actions

Ingestion of sodium gluconate is known to stimulate the production of intestinal butyrate. It is widely used in food, pharmaceutical paper and textile industry. It acts as a chelating agent. Sodium gluconate serves as a detergent in bottle washing formulation.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Potassium gluconate United States Pharmacopeia (USP) Reference Standard

USP

1550001

Potassium gluconate

Sodium Stibogluconate A pentavalent antimony compound that irreversibly inhibits protein tyrosine phosphatase (PTPase) activity, including Src homology PTPase-1 (SHP-1) (99% inhibition at ~11 µM) by forming a stable complex.

Sigma-Aldrich

567565

Sodium Stibogluconate

Gluconic acid (50% solution in water) for synthesis

Sigma-Aldrich

8.22057

Gluconic acid

Gluconic acid: Properties, applications and microbial production.
Ramachandran S, et al.
Food Technology and Biotechnology, 44(2) (2006)
Influence of nitrate and nitrite on thyroid hormone responsive and stress-associated gene expression in cultured Rana catesbeiana tadpole tail fin tissue
Hinther A, et al.
Frontiers in Genetics, 3, 51-51 (2012)
Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production
Kameue C, et al.
The Journal of Nutrition, 134(4), 940-944 (2004)
Two-electrode voltage-clamp recordings in Xenopus laevis oocytes: reconstitution of abscisic acid activation of SLAC1 anion channel via PYL9 ABA receptor
Wang C, et al.
Bio-protocol, 7(2) (2017)
Elena von Molitor et al.
Cell calcium, 87, 102164-102164 (2020-02-06)
Bridging the gap between two-dimensional cell cultures and complex in vivo tissues, three-dimensional cell culture models are of increasing interest in the fields of cell biology and pharmacology. However, present challenges hamper live cell imaging of three-dimensional cell cultures. These
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