SMB01360
1-MethylpseudoUridine
≥98% (HPLC)
Synonym(s):
1-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, N1-Methylpseudouridine
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About This Item
Empirical Formula (Hill Notation):
C10H14N2O6
CAS Number:
Molecular Weight:
258.23
MDL number:
UNSPSC Code:
41106305
NACRES:
NA.21
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
solid
storage temp.
2-8°C
InChI
1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1
InChI key
UVBYMVOUBXYSFV-XUTVFYLZSA-N
General description
A key aspect of COVID-19 mRNA vaccines is the use of the modified nucleobase Methylpseudouridine to increase their effectiveness. The modified nucleobase helps cloak mRNA vaccines from the immune system, limiting their undesired immune stimulation, and in certain circumstances may also enhance the synthesis of antigens.
Application
Vaccine development
Other Notes
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wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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