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T0891

Supelco

Tolbutamide

analytical standard

Synonym(s):

1-Butyl-3-(4-methylphenylsulfonyl)urea, N-[(Butylamino)carbonyl]-4-methylbenzenesulfonamide

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About This Item

Empirical Formula (Hill Notation):
C12H18N2O3S
CAS Number:
64-77-7
Molecular Weight:
270.35
Beilstein/REAXYS Number:
1984428
EC Number:
200-594-3
MDL number:
MFCD00027169
UNSPSC Code:
41116107
PubChem Substance ID:
329826629
NACRES:
NA.24

biological source

synthetic (organic)

Quality Level

200

grade

analytical standard

assay

97.0-103.0%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

ethanol: 50 mg/mL, clear, colorless

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)

InChI key

JLRGJRBPOGGCBT-UHFFFAOYSA-N

Gene Information

human ... ABCC8(6833) , ALB(213) , CYP1A2(1544) , CYP2C9(1559) , EPHX2(2053) , KCNJ1(3758) , KCNJ11(3767)
mouse ... Ephx2(13850)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Anti-diabetic agent. Metabolized by CYP2C9 (tolbutamide hydroxylase).

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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