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W245735

Sigma-Aldrich

Ethyl pyruvate

≥97%, FG

Synonym(s):

Ethyl 2-oxopropanoate, Ethyl 2-oxopropionate, Ethyl acetyl formate, Ethyl pyroracemate, Pyruvic acid ethyl ester

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About This Item

Linear Formula:
CH3COCOOC2H5
CAS Number:
Molecular Weight:
116.12
FEMA Number:
2457
Beilstein/REAXYS Number:
1071466
EC Number:
Council of Europe no.:
430
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.442

biological source

synthetic

Quality Level

grade

FG
Halal
Kosher

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

assay

≥97%

refractive index

n20/D 1.404 (lit.)

bp

144 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

fruity; ethereal; rum; sweet

SMILES string

CCOC(=O)C(C)=O

InChI

1S/C5H8O3/c1-3-8-5(7)4(2)6/h3H2,1-2H3

InChI key

XXRCUYVCPSWGCC-UHFFFAOYSA-N

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Related Categories

Application


  • High mobility group box 1 in the central nervous system: regeneration hidden beneath inflammation.: This study explores the role of high mobility group box 1 (HMGB1) in the central nervous system, focusing on its regenerative capabilities despite its inflammatory properties. Ethyl pyruvate was identified as a potential therapeutic agent in mitigating inflammation and promoting neural regeneration (Kim et al., 2025).

  • Immunomodulation of Ethyl pyruvate on gestational diabetes mellitus in Mice; The impact on Th17/Treg balance.: This study investigates the effects of ethyl pyruvate on gestational diabetes mellitus (GDM) in mice, focusing on its immunomodulatory effects and its impact on the Th17/Treg balance, highlighting its potential benefits in managing GDM (Zhao et al., 2024).

  • HMGB1/RAGE axis in tumor development: unraveling its significance.: The review delves into the HMGB1/RAGE axis in tumor development, examining its significance and the potential therapeutic role of ethyl pyruvate in targeting this pathway to inhibit tumor growth and progression (Fan et al., 2024).

  • Ethyl pyruvate ameliorates acute respiratory distress syndrome in mice.: This article highlights the therapeutic potential of ethyl pyruvate in ameliorating acute respiratory distress syndrome (ARDS) in a mouse model, showcasing its anti-inflammatory and protective effects (Micanovic et al., 2024).

pictograms

FlameCorrosion

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup


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