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Sigma-Aldrich

3-(2-Furoyl)quinoline-2-carboxaldehyde

suitable for fluorescence, ≥95% (HPLC), BioReagent

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About This Item

Empirical Formula (Hill Notation):
C15H9NO3
CAS Number:
126769-01-5
Molecular Weight:
251.24
MDL number:
MFCD03427748
UNSPSC Code:
12171500
PubChem Substance ID:
57647686
NACRES:
NA.32

product line

BioReagent

Quality Level

100

assay

≥95% (HPLC)

form

powder

solubility

methanol: soluble

fluorescence

λex 486 nm; λem ~600 nm in 0.1 M sodium borate pH 9.0 (after derivatization with glycine)

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

[H]C(=O)c1nc2ccccc2cc1C(=O)c3ccco3

InChI

1S/C15H9NO3/c17-9-13-11(15(18)14-6-3-7-19-14)8-10-4-1-2-5-12(10)16-13/h1-9H

InChI key

PNCHURHVMDRFTR-UHFFFAOYSA-N

General description

3-(2-Furoyl)quinoline-2-carboxaldehyde is a neutral fluorogenic probe for amines for the picomolar assay of proteins by capillary electrophoresis (CE).

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tingting Zhao et al.
Electrophoresis, 42(4), 350-359 (2020-11-29)
A quantitative method was developed for the direct identity confirmation and quantification of alendronate using CE-MS combined with a pH-assisted focusing technique, dynamic pH barrage junction focusing. A pH-induced variation in electrophoretic mobility led to online focusing of alendronate at
Alexander V Stoyanov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 780(2), 283-287 (2002-10-29)
Fluorogenic reagents are used for protein labeling when high-sensitivity fluorescence detection is required. Similar to traditional labeling with activated fluorescent dyes, such as fluorescein isothiocyanate, a fluorogenic reaction is expected to change the physical-chemical properties of proteins. Knowledge of these
Juan Feng et al.
Electrophoresis, 29(2), 475-482 (2007-12-08)
Carbonyl-modified proteins are markers of oxidative damage. Here, we report a new method for detecting and quantifying carbonylated proteins by capillary sieving electrophoresis (CSE) with LIF detection (CSE-LIF). Alexa 488 hydrazide is used for the specific labeling of carbonyls while
David A Michels et al.
Analytical chemistry, 79(15), 5963-5971 (2007-06-27)
A fast and improved sample preparation scheme was developed for protein analysis using capillary electrophoresis-sodium dodecyl sulfate (CE-SDS) with laser-induced fluorescence detection. This CE-SDS method was developed as a purity assay for recombinant monoclonal antibodies (rMAbs). In this assay, rMAbs
Melissa M Harwood et al.
Electrophoresis, 28(6), 932-937 (2007-02-20)
The composition of single MCF-7 breast cancer cells is characterized using 2-D CE. Individual MCF-7 cells were aspirated into a 30 mum inner diameter fused-silica capillary and lysed by contact with an SDS-containing buffer. Proteins and other primary amines were
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