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302R-1

Sigma-Aldrich

Neurofilament (EP79) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP79, monoclonal

description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

form

buffered aqueous solution

species reactivity

human

packaging

bottle of 1.0 mL predilute (302R-17)
bottle of 7.0 mL predilute (302R-18)
vial of 0.1 mL concentrate (302R-14)
vial of 0.5 mL concentrate (302R-15)
vial of 1.0 mL concentrate (302R-16)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... NEFL(4747)

Related Categories

General description

Immunolabelling of neurofilaments (NF) is employed for study of nerve distribution of normal and abnormal tissues, and neuronal differentiation of neoplasms. NF are found in neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, neuroblastomas, and retinoblastomas. Neurofilaments are also present in paragangliomas, as well as, adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and lung small cell carcinoma also express neurofilament.1-5

Quality


IVD
IVD
IVD
RUO

Linkage

Neurofilament Positive Control Slides, Product No. 302S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Expression of neurofilament antigens by normal and neoplastic human adrenal chromaffin cells.
J Q Trojanowski et al.
The New England journal of medicine, 313(2), 101-104 (1985-07-11)
M Miettinen et al.
Laboratory investigation; a journal of technical methods and pathology, 52(4), 429-436 (1985-04-01)
Twelve cases of gastrointestinal neuroendocrine tumors, including eight carcinoids and four pancreatic islet cell tumors or their metastases, were immunohistochemically analyzed for the expression of different types of intermediate filament proteins. All of the tumors showed cytokeratin positivity in immunostaining
C D Morrison et al.
Seminars in diagnostic pathology, 17(3), 204-215 (2000-09-01)
The diagnosis and evaluation of neoplasms of the central nervous system frequently involves the use of immunohistochemical stains. This article reviews some of the more commonly used markers including glial fibrillary acidic protein, synaptophysin, neurofilament protein, S-100 protein, epithelial membrane

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