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329M-9

Sigma-Aldrich

Renal Cell Carcinoma (PN-15) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

PN-15, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (329M-94)
vial of 0.5 mL concentrate (329M-95)
bottle of 1.0 mL predilute (329M-97)
vial of 1.0 mL concentrate (329M-96)
bottle of 7.0 mL predilute (329M-98)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG1κ

control

renal cell carcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic, membranous

Related Categories

General description

Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with approximately 90% of primary renal cell carcinomas and approximately 85% of metastatic renal cell carcinomas. Other tumors that may react with this antibody are parathyroid adenoma and an occasional breast carcinoma. Nephroblastoma, oncocytoma, mesoblasticnephroma, transitional cell carcinoma, and angiomyolipoma are not labeled with this antibody.
Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with most primary renal cell carcinomas and can aid in the diagnosis when renal cell carcinoma enters the differential diagnosis.

Quality


IVD
IVD
IVD
RUO

Linkage

Renal Cell Carcinoma Positive Control Slides, Product No. 329S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

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Neriman Gokden et al.
Applied immunohistochemistry & molecular morphology : AIMM, 11(2), 116-119 (2003-06-05)
Renal cell carcinoma (RCC) not uncommonly presents with metastases and causes diagnostic difficulty to the cytopathologist who is involved in the initial diagnostic workup of tumors with an unknown primary site. RCC marker (RCC Ma) recognizes a human proximal tubule
A K Avery et al.
The American journal of surgical pathology, 24(2), 203-210 (2000-02-19)
The majority of renal neoplasms can be distinguished on the basis of histologic examination alone; however, there are morphologic similarities between clear cell renal carcinoma and chromophobe cell carcinoma, as well as between the granular/eosinophilic variants of these tumors and
D K McGregor et al.
The American journal of surgical pathology, 25(12), 1485-1492 (2001-11-22)
The diagnosis of primary or metastatic renal cell carcinoma (RCC) can be difficult, especially in small biopsies, because of the wide variety of histologic appearances and clinical presentations that RCC can assume. An immunomarker specific for RCC is currently not

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