Skip to Content
MilliporeSigma
All Photos(1)

Documents

44714

Sigma-Aldrich

(S)-Mevalonic acid lithium salt

≥96.0% (GC)

Synonym(s):

Lithium (S)-3,5-dihydroxy-3-methyl-pentanoate, Lithium (S)-3,5-dihydroxy-3-methyl-valerate, S-MVA-Li

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H12O4 · xLi+
CAS Number:
32451-23-3
Molecular Weight:
148.16 (free acid basis)
UNSPSC Code:
12352106

Quality Level

100

assay

≥96.0% (GC)

optical activity

[α]/D +25.0±3.0°, c = 0.1 in 1 M HCl

storage temp.

2-8°C

InChI

1S/C6H12O4/c1-6(10,2-3-7)4-5(8)9/h7,10H,2-4H2,1H3,(H,8,9)/t6-/m0/s1

InChI key

KJTLQQUUPVSXIM-LURJTMIESA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

Farnesyl pyrophosphate ammonium salt methanol:ammonia solution, ≥95% (TLC)

Sigma-Aldrich

F6892

Farnesyl pyrophosphate ammonium salt

Geranyl pyrophosphate lithium salt ≥95.0% (TLC)

Sigma-Aldrich

76532

Geranyl pyrophosphate lithium salt

Simvastatin ≥97% (HPLC), solid

Sigma-Aldrich

S6196

Simvastatin

HMG-CoA Reductase Assay Kit sufficient for 30 assays (1 mL), sufficient for 100 assays (200 μL)

Sigma-Aldrich

CS1090

HMG-CoA Reductase Assay Kit

Geranyl pyrophosphate ammonium salt 1 mg/mL in methanol (:aqueous 10 mM NH4OH (7:3)), ≥95% (TLC)

Sigma-Aldrich

G6772

Geranyl pyrophosphate ammonium salt

R R Kopito et al.
Journal of lipid research, 23(4), 577-583 (1982-05-01)
A circadian rhythm in plasma mevalonate was identified in human subjects. This variation, over a 5-fold range, is paralleled by a rhythm in urinary excretion. No such diurnal change in plasma mevalonate was observed in schedule-fed, light-cycled rats, despite the
R A Larson et al.
Blood, 64(1), 257-262 (1984-07-01)
Mevalonic acid can stimulate leukemic cells from some patients with B cell chronic lymphocytic leukemia (CLL) to enter the cell cycle in vitro and to synthesize DNA. Unlike normal human peripheral blood lymphocytes, which require the presence of granulocytes for
Le-Le Hu et al.
PloS one, 6(12), e29491-e29491 (2012-01-06)
Given a compound, how can we effectively predict its biological function? It is a fundamentally important problem because the information thus obtained may benefit the understanding of many basic biological processes and provide useful clues for drug design. In this
Priti Agarwal et al.
The Journal of investigative dermatology, 135(4), 1080-1088 (2014-12-19)
Vitiligo is a common autoimmune disease of the skin that results in disfiguring white spots. There are no Food and Drug Administration (FDA)-approved treatments, and current treatments are time-consuming, expensive, and of low efficacy. We sought to identify new treatments

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service