Skip to Content
MilliporeSigma
All Photos(5)

Documents

C6445

Sigma-Aldrich

Sodium cholate hydrate

BioXtra, ≥99%

Synonym(s):

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

Sign Into View Organizational & Contract Pricing
All Photos(5)

About This Item

Empirical Formula (Hill Notation):
C24H39NaO5 · xH2O
CAS Number:
206986-87-0
Molecular Weight:
430.55 (anhydrous basis)
Beilstein/REAXYS Number:
3582354
EC Number:
206-643-5
MDL number:
MFCD00150749
UNSPSC Code:
12161900
PubChem Substance ID:
24892867
NACRES:
NA.25

description

anionic

Quality Level

200

product line

BioXtra

assay

≥99%

form

powder

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

impurities

≤0.05% Phosphorus (P)
≤0.1% Insoluble matter

CMC

9-15 mM (20-25°C)

solubility

H2O: 1 M, clear, faintly yellow to yellow

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

HLB

18

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

InChI key

MUVVIYFKOVLQHL-RCVKHMDESA-M

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins.

Application

Sodium cholate hydrate has been used in a study to assess infiltration of pressurized promoter solutions in a mesoporous silica.
Sodium cholate hydrate has been used:
  • as a component of biofilm growth media along with tryptic soy broth (TSB) to test the effects of each bile salt on biofilm formation
  • as a detergent to study its effect on cannabinoid receptor 1 (CB1) detection by western blot
  • as a promoter to prepare solution B for the synthesis of tungsten disulfide (WS2) on a SiO2/Si wafer

Features and Benefits

  • pH range 5-8
  • Suitable for membrane technology and culture media

hcodes

H412

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 7

1 of 7

Sodium glycocholate hydrate ≥95% (TLC)

Sigma-Aldrich

G7132

Sodium glycocholate hydrate

Membrane Scaffold Protein 1D1 recombinant, expressed in E. coli

Sigma-Aldrich

M6574

Membrane Scaffold Protein 1D1

Sodium deoxycholate BioXtra, ≥98.0% (dry matter, NT)

Sigma-Aldrich

30970

Sodium deoxycholate

Millipore

Millipore

B8756

Bile salts

Sodium taurocholate BRP, European Pharmacopoeia (EP) Reference Standard

S0900000

Sodium taurocholate

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine ≥95.5% (GC), ≥98% (TLC)

Sigma-Aldrich

P3017

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine

Membrane Scaffold Protein 2N2 recombinant, expressed in E. coli, MSP1D1-MSP1D2 fusion protein

Sigma-Aldrich

MSP12

Membrane Scaffold Protein 2N2

F Peter Guengerich et al.
Nature protocols, 4(9), 1245-1251 (2009-08-08)
Cytochrome P450 (P450) enzymes are important in the metabolism of steroids, vitamins, carcinogens, drugs and other compounds. Two of the commonly used assays in this field are the measurements of total P450 and NADPH-P450 reductase in biological preparations. A detailed
Infiltration of pressurized promoter solutions in a mesoporous silica
Punyamurtula and Qiao
Microporous Mater., 103, 5-5 (2007)
Fang Fang et al.
Journal of bacteriology, 191(18), 5743-5757 (2009-07-14)
Commensal lactobacilli frequently produce bile salt hydrolase (Bsh) enzymes whose roles in intestinal survival are unclear. Twenty-six Lactobacillus salivarius strains from different sources all harbored a bsh1 allele on their respective megaplasmids. This allele was related to the plasmid-borne bsh1
Volkan K Köseoğlu et al.
Infection and immunity, 87(7) (2019-04-17)
Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism. Here, we
Thuc Hue Ly et al.
Nature communications, 7, 10426-10426 (2016-01-28)
Grain boundaries in monolayer transition metal dichalcogenides have unique atomic defect structures and band dispersion relations that depend on the inter-domain misorientation angle. Here, we explore misorientation angle-dependent electrical transport at grain boundaries in monolayer MoS2 by correlating the atomic
View All Related Papers

Protocols

Single-walled Carbon Nanotubes: Exfoliation and Debundling Procedure

The dispersibility and bundle defoliation of single-walled carbon nanotubes (SWCNTs), which can be applied to materials produced by the CoMoCAT® process, have been extensively investigated by SouthWest NanoTechnologies (SWeNT ®) and at the University of Oklahoma.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service