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A3256

Sigma-Aldrich

L-(+)-Arabinose

≥99% (GC)

Synonym(s):

(+)-Arabinose

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
5328-37-0
Molecular Weight:
150.13
Beilstein/REAXYS Number:
1723085
EC Number:
226-214-6
MDL number:
MFCD00135866
UNSPSC Code:
12352201
PubChem Substance ID:
24890753
NACRES:
NA.25

Quality Level

300

assay

≥99% (GC)

form

powder

optical activity

[α]/D +103 to +105°°(lit.)

technique(s)

flow cytometry: suitable
gas chromatography (GC): suitable
ion chromatography: suitable
microbiological culture: suitable

color

white to off-white

mp

160-163 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

suitability

suitable for determination of protein concentration
suitable for microtiter plates

application(s)

genomic analysis
life science and biopharma
microbiology

SMILES string

OC[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4-,5+/m0/s1

InChI key

PYMYPHUHKUWMLA-VAYJURFESA-N

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General description

L-(+)-Arabinose, a five-carbon sugar found widely in nature, plays a pivotal role in biochemical research, particularly in microbiology and biomedicine. In microbial culture, it serves as a sole carbon source for various bacteria, as many bacteria contain an inducible arabinose operon, allowing them to utilize L-arabinose as a primary carbon source. This characteristic has made arabinose indispensable in microbiological tests, including the arabinose test, which assesses a microbe′s ability to ferment arabinose.Beyond microbiology, L-arabinose has gained significance in the biomedicine industry due to its potential in drug delivery and metabolic disorder research, particularly in the treatment of conditions like diabetes. This natural sugar shows promise in regulating blood glucose levels and possesses antimicrobial properties, making it a subject of investigation in the fight against bacterial infections. Additionally, L-arabinose is utilized in protein expression studies, serving as a one-way switch for regulating gene expression.

Application

L-Arabinose can be used as a substrate to identify, differentiate and characterize pentose sugar isomerase(s) and in the bioproduction of L-ribose.
L-Arabinose has been used

  • to induce and regulate the expression of specific genes or proteins in bacterial strains

Biochem/physiol Actions

L-Arabinose is the naturally occurring isomer and is a constituent of plant polysaccharides. Most bacteria contain an inducible arabinose operon that codes for a series of enzymes and transporters that allows L-arabinose to be used as the sole carbon source in microbial culture.

Features and Benefits

  • Suitable for biochemical and cell culture research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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flash_point_c

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wolf-Dieter Reiter
Current opinion in plant biology, 11(3), 236-243 (2008-05-20)
During the past few years, substantial progress has been made to understand the enzymology and regulation of nucleotide sugar interconversion reactions that are irreversible in vivo on thermodynamic grounds. Feedback inhibition of enzymes by metabolic end products appears to be
M Helanto et al.
Applied microbiology and biotechnology, 83(1), 77-83 (2009-01-20)
L-Ribose is a rare and expensive sugar that can be used as a precursor for the production of L-nucleoside analogues, which are used as antiviral drugs. In this work, we describe a novel way of producing L-ribose from the readily
Koen J T Venken et al.
Nucleic acids research, 36(18), e114-e114 (2008-08-05)
Studying gene function in the post-genome era requires methods to localize and inactivate proteins in a standardized fashion in model organisms. While genome-wide gene disruption and over-expression efforts are well on their way to vastly expand the repertoire of Drosophila
Wei Lin et al.
Molecular cell, 70(1), 60-71 (2018-04-03)
Fidaxomicin is an antibacterial drug in clinical use for treatment of Clostridium difficile diarrhea. The active ingredient of fidaxomicin, lipiarmycin A3 (Lpm), functions by inhibiting bacterial RNA polymerase (RNAP). Here we report a cryo-EM structure of Mycobacterium tuberculosis RNAP holoenzyme in
Tobias Bergmiller et al.
BMC microbiology, 11, 118-118 (2011-05-31)
The essential Escherichia coli gene ygjD belongs to a universally conserved group of genes whose function has been the focus of a number of recent studies. Here, we put ygjD under control of an inducible promoter, and used time-lapse microscopy
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