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AV31443

Sigma-Aldrich

Anti-HHEX antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Hematopoietically expressed homeobox

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

30 kDa

species reactivity

human, horse, rat, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_002720

UniProt accession no.

Q03014

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HHEX(3087)

General description

HHEX is a homeobox protein that is involved in developmental functions. HHEX variations have been identified as risk factors for diabetes type 2 in Japanese population groups.
Rabbit Anti-HHEX antibody recognizes pig, human, canine, bovine, mouse, and rat HHEX.

Immunogen

Synthetic peptide directed towards the middle region of human HHEX

Application

Rabbit Anti-HHEX antibody is suitable for use in western blot (0.5μg/ml) and immunohistochemistry (4-8μg/ml) applications.

Biochem/physiol Actions

HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.

Sequence

Synthetic peptide located within the following region: KQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQED

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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M Horikoshi et al.
Diabetologia, 50(12), 2461-2466 (2007-10-12)
Recently, several groups have carried out whole-genome association studies in European and European-origin populations and found novel type 2 diabetes-susceptibility genes, fat mass and obesity associated (FTO), solute carrier family 30 (zinc transporter), member 8 (SLC30A8), haematopoietically expressed homeobox (HHEX)

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