Skip to Content
MilliporeSigma
All Photos(1)

Documents

B7438

Sigma-Aldrich

6-B345TTQ

>98% (HPLC)

Synonym(s):

6-Bromo-3,4-dihydro-4-(3,4,5-trimethoxyphenyl)-benzo[h]quinolin-2(1H)-one

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H20BrNO4
CAS Number:
297157-87-0
Molecular Weight:
442.30
MDL number:
MFCD01988835
UNSPSC Code:
12352200
PubChem Substance ID:
329773295
NACRES:
NA.77

Quality Level

100

assay

>98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥20 mg/mL

storage temp.

2-8°C

SMILES string

COc1cc(cc(OC)c1OC)C2CC(=O)Nc3c2cc(Br)c4ccccc34

InChI

1S/C22H20BrNO4/c1-26-18-8-12(9-19(27-2)22(18)28-3)15-11-20(25)24-21-14-7-5-4-6-13(14)17(23)10-16(15)21/h4-10,15H,11H2,1-3H3,(H,24,25)

InChI key

KPOXOTVERMGJQS-UHFFFAOYSA-N

Biochem/physiol Actions

6-B345TTQ is a non-cytotoxic inhibitor of α4 integrin paxillin interaction.

pictograms

Environment
GHS09

signalword

Warning

hcodes

H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jordan J Toutounchian et al.
Molecular pharmacology, 91(1), 1-13 (2016-12-04)
Targeting vascular endothelial growth factor (VEGF) is a common treatment strategy for neovascular eye disease, a major cause of vision loss in diabetic retinopathy and age-related macular degeneration. However, the decline in clinical efficacy over time in many patients suggests
Daniela Alfano et al.
Human molecular genetics, 28(14), 2295-2308 (2019-06-11)
Tbx1, the major candidate gene for DiGeorge or 22q11.2 deletion syndrome, is required for efficient incorporation of cardiac progenitors of the second heart field (SHF) into the heart. However, the mechanisms by which TBX1 regulates this process are still unclear.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service