Skip to Content
MilliporeSigma
All Photos(1)

Documents

C113060

Sigma-Aldrich

DMT-dC(ac) Phosphoramidite

configured for ABI

Synonym(s):

DMT-dC(ac) Amidite, N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N4-Acetyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C41H50N5O8P
CAS Number:
154110-40-4
Molecular Weight:
771.84
MDL number:
MFCD09842112
UNSPSC Code:
12352200
PubChem Substance ID:
329774866
NACRES:
NA.51

biological source

non-animal source (no BSE/TSE risk)

Quality Level

200

type

for DNA synthesis

product line

Proligo Reagents

assay

≥98% (31P-NMR)
≥99.0% (reversed phase HPLC)

form

powder

technique(s)

oligo synthesis: suitable

color

white to off-white

λ

conforms (UV/VIS Identity)

compatibility

configured for ABI

nucleoside profile

base: deoxycytidine
base protecting group: acetyl
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard

storage temp.

-10 to -25°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(C)=O)=NC3=O)(c4ccccc4)c5ccc(OC)cc5

InChI

1S/C41H50N5O8P/c1-28(2)46(29(3)4)55(52-25-11-23-42)54-36-26-39(45-24-22-38(43-30(5)47)44-40(45)48)53-37(36)27-51-41(31-12-9-8-10-13-31,32-14-18-34(49-6)19-15-32)33-16-20-35(50-7)21-17-33/h8-10,12-22,24,28-29,36-37,39H,11,25-27H2,1-7H3,(H,43,44,47,48)/t36-,37+,39+,55?/m0/s1

InChI key

MECWEBCHRKVTNV-RLWDVSNXSA-N

Looking for similar products? Visit Product Comparison Guide

General description

DMT-dC(ac) phosphoramidite is a DNA phosphoramidite that belongs to the group of fast deprotection phosphoramidite.The key features of dC(ac) are as follows:
  • Ultrafast deprotection: 10 minutes at 65°C with AMA reagent
  • Key component in oligonucleotide synthesis
  • Industry-standard for fast deprotection chemistry
  • Operating for AMA deprotection methods without changes
  • Consistent lot-to-lot high purity and performance
  • Manufactured under a certified ISO 9001 quality system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service