Skip to Content
MilliporeSigma
All Photos(1)

Documents

C4740

Sigma-Aldrich

Cisapride monohydrate

≥98% (HPLC), solid

Synonym(s):

cis-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenxamide monohydrate, Acenalin, Cipril

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C23H29N3O4ClF · H2O
CAS Number:
260779-88-2
Molecular Weight:
483.96
EC Number:
279-689-7
MDL number:
MFCD03305346
UNSPSC Code:
12352200
PubChem Substance ID:
329775068
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

solid

color

white

solubility

DMSO: ~30 mg/mL

originator

Johnson & Johnson

SMILES string

O.CO[C@@H]1CN(CCCOc2ccc(F)cc2)CC[C@@H]1NC(=O)c3cc(Cl)c(N)cc3OC

InChI

1S/C23H29ClFN3O4.H2O/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16;/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29);1H2/t20-,22+;/m0./s1

InChI key

QBYYXIDJOFZORM-IKGOIYPNSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochem/physiol Actions

5-HT4 serotonin receptor agonist.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 8

1 of 8

Quinidine anhydrous

Sigma-Aldrich

Q3625

Quinidine

Pimozide

Sigma-Aldrich

P1793

Pimozide

Domperidone powder, ≥98% (HPLC)

Sigma-Aldrich

D122

Domperidone

(±)-Sotalol hydrochloride ≥98% (TLC), powder

Sigma-Aldrich

S0278

(±)-Sotalol hydrochloride

Nifedipine ≥98% (HPLC), powder

Sigma-Aldrich

N7634

Nifedipine

(±)-Verapamil hydrochloride ≥99% (titration), powder

Sigma-Aldrich

V4629

(±)-Verapamil hydrochloride

Chlorpromazine hydrochloride ≥98% (TLC)

Sigma-Aldrich

C8138

Chlorpromazine hydrochloride

Adenosine 5′-triphosphate magnesium salt ≥95%, bacterial

Sigma-Aldrich

A9187

Adenosine 5′-triphosphate magnesium salt

M R Briejer et al.
The Journal of pharmacology and experimental therapeutics, 274(2), 641-648 (1995-08-01)
In the guinea pig proximal colon, 5-hydroxytryptamine (5-HT) stimulates neuronal 5-HT1-like receptors to induce relaxations that are mediated by nitric oxide and ATP. In the current study, the effects of cisapride and structural analogs on these 5-HT-induced relaxations were investigated.
Mihai Covasa et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 285(3), R641-R648 (2003-05-31)
MK-801, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, enhances gastric emptying while increasing food intake. Although our previously reported results implicate the vagus in MK-801's effect on feeding, it is not clear whether vagal motor fibers participate in the feeding response.
Atsuko Inui et al.
Japanese journal of pharmacology, 90(4), 313-320 (2002-12-26)
It is known that 5-HT(4) receptors in the colon of guinea pigs show a distribution similar to that in humans. Thus, we examined the effects of mosapride citrate (mosapride) and cisapride, two 5-HT(4)-receptor agonists, on colonic motility in conscious guinea
Haruka Nishimuta et al.
The AAPS journal, 21(2), 20-20 (2019-01-24)
Accurate prediction of human pharmacokinetics for drugs remains challenging, especially for non-cytochrome P450 (P450) substrates. Hepatocytes might be suitable for predicting hepatic intrinsic clearance (CLint) of new chemical entities, because they can be applied to various compounds regardless of the
Henry C Liu et al.
The Journal of pharmacology and experimental therapeutics, 359(1), 215-229 (2016-08-05)
Statistical analysis was performed on physicochemical descriptors of ∼250 drugs known to interact with one or more SLC22 "drug" transporters (i.e., SLC22A6 or OAT1, SLC22A8 or OAT3, SLC22A1 or OCT1, and SLC22A2 or OCT2), followed by application of machine-learning methods
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service