Skip to Content
MilliporeSigma
All Photos(2)

Documents

C5041

Sigma-Aldrich

6-Carboxyfluorescein diacetate

≥95% (HPLC)

Synonym(s):

6-CFDA, 6-Carboxy-di-O-acetylfluorescein

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C25H16O9
CAS Number:
Molecular Weight:
460.39
Beilstein/REAXYS Number:
67043
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Quality Level

100
200

assay

≥95% (HPLC)

form

powder

color

white to yellow

solubility

chloroform/ethanol (1:1): 9.80-10.20 mg/mL, clear, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1

InChI

1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)

InChI key

QMOGCCYGOPYYNT-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

6-Carboxyfluorescein diacetate has been used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin.
Fluorescent wavelengths λex 492nm; λemm 517nm in 0.1M Tris, pH 8.0.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Chander Parkash Dora et al.
International journal of pharmaceutics, 530(1-2), 113-127 (2017-07-26)
The aim of the present research is to increase lipid solubility, metabolic stability and therapeutic efficacy of water soluble gemcitabine (GEM) via phospholipid complex (PC) formation. A novel phospholipid complex of GEM was successfully prepared and optimized. Physical interaction of
Douglas E Brenneman et al.
Journal of molecular neuroscience : MN, 47(2), 368-379 (2012-04-27)
Severe seizure activity is associated with recurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention to halt these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. In the
G Ricci et al.
Human reproduction (Oxford, England), 17(10), 2665-2672 (2002-09-28)
Apoptosis plays an important role in regulating spermatogenesis. However, the biological significance of apoptosis in ejaculated sperm is not yet clear. This study set out to investigate how apoptosis correlates with semen quality and the presence of seminal leukocytes. Fifty-seven
Evaluation of sperm quality snakes Erythrolamprus poecilogyrus sublineatus (Cope, 1860) (Serpentes, Dipsadidae).
Silva AC, et al.
Brazilian journal of biology = Revista brasleira de biologia, doi: 10-doi: 10 (2017)
Garry R Smith et al.
Journal of molecular neuroscience : MN, 52(3), 446-458 (2013-11-28)
Severe seizure activity is associated with reoccurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention with these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. We have optimized

Articles

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service