Skip to Content
MilliporeSigma
All Photos(1)

Documents

C5135

Sigma-Aldrich

Castor Oil, Ethoxylated

pH range 6.0-8.0

Synonym(s):

Cremophor® EL, EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil

Sign Into View Organizational & Contract Pricing


About This Item

CAS Number:
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25

description

non-ionic

Quality Level

form

liquid

mol wt

~2500 g/mol

pH range

6.0-8.0

HLB

12 - 14

application(s)

sample preservation

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Castor Oil, Ethoxylated is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Castor Oil, Ethoxylated is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.

Application

Castor Oil, Ethoxylated has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.

Biochem/physiol Actions

Castor Oil, Ethoxylated is used in lipid-based formulations for drugs and solubilization of cosmetics. Castor Oil, Ethoxylated is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.

Other Notes

A derivative of castor oil and ethylene oxide.

Legal Information

Cremophor is a registered trademark of BASF SE

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 6

1 of 6

Kollisolv® PEG E 400

Sigma-Aldrich

06855

Kollisolv® PEG E 400

Sigma-Aldrich

Sigma-Aldrich

83912

Castor oil

Poloxamer 407 oxyethylene 71.5-74.9 %

Sigma-Aldrich

62035

Poloxamer 407

Poloxamer 188 solid

Sigma-Aldrich

K4894

Poloxamer 188

USP

USP

1096826

Castor oil

Independent evaluation of the anatomical and behavioral effects of Taxol in rat models of spinal cord injury.
Popovich PG
Experimental Neurology, 261, 97-97 (2014)
Large-scale imaging of cortical network activity with calcium indicators.
Ikegaya Y
Neuroscience Research, 52, 132-132 (2005)
Colloidal nanocarriers for the enhanced cutaneous delivery of naftifine: characterization studies and in vitro and in vivo evaluations
Erdal MS, et al.
International journal of nanomedicine, 11, 1027-1027 (2016)
A nonionic polyethylene oxide (PEO) surfactant model: experimental and molecular dynamics studies of Kolliphor EL
Suys EJA, et al.
Journal of Pharmaceutical Sciences, 108(1), 193-204 (2019)
Triiodothyronine reverses depressed contractile performance after excessive catecholamine stimulation.
Timek T
The Annals of Thoracic Surgery, 66, 1618-1618 (1998)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service