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C6070

Sigma-Aldrich

CAPS

BioXtra, ≥99%

Synonym(s):

3-(Cyclohexylamino)-1-propanesulfonic acid

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About This Item

Linear Formula:
C6H11NH(CH2)3SO3H
CAS Number:
Molecular Weight:
221.32
Beilstein/REAXYS Number:
2835588
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

product line

BioXtra

Quality Level

assay

≥99%

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

pH

3.0-7.0 (20 °C, 0.5 M in H2O)

pKa (25 °C)

10.4

pKa 

10.4

mp

>300 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

absorption

≤0.2 at 260 in H2O at 0.5 M
≤0.2 at 280 in H2O at 0.5 M

storage temp.

room temp

SMILES string

OS(=O)(=O)CCCNC1CCCCC1

InChI

1S/C9H19NO3S/c11-14(12,13)8-4-7-10-9-5-2-1-3-6-9/h9-10H,1-8H2,(H,11,12,13)

InChI key

PJWWRFATQTVXHA-UHFFFAOYSA-N

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Application


  • Lignin degradation by a novel thermophilic and alkaline yellow laccase from Chitinophaga sp.: This study highlights the application of CAPS buffer in stabilizing enzymes under extreme conditions for industrial lignin degradation. The use of CAPS enhances the stability and activity of laccase, pivotal for bio-refining processes (Buzzo et al., 2024).

  • Improved Refolding of a Human IgG1 Fc (CH2-CH3) Scaffold from Its Inclusion Body in E. coli by Alkaline Solubilization.: Research demonstrates CAPS buffer′s critical role in the solubilization and refolding of recombinant proteins. This advancement is significant for therapeutic protein production, ensuring higher yield and functionality (Ishikawa et al., 2022).

  • An optimized SDS-PAGE protocol with a new blotting system for the initial testing procedure of ESAs in doping control.: This paper utilizes CAPS buffer in the development of a new SDS-PAGE blotting system for doping tests, offering more reliable and faster detection of erythropoiesis-stimulating agents in sports (Martin et al., 2022).

  • Insight into organophosphate chemical warfare agent simulant hydrolysis in metal-organic frameworks.: The study uses CAPS buffer to investigate the hydrolysis reactions of chemical warfare agents in metal-organic frameworks. This research is crucial for developing materials that can neutralize hazardous agents safely and efficiently (Ploskonka and DeCoste, 2019).

  • Complexometric and argentometric titrations using thread-based analytical devices.: CAPS buffer is applied in novel thread-based analytical devices for environmental monitoring. These devices, utilizing complexometric and argentometric titrations, offer a portable, cost-effective solution for on-site water quality analysis (Jarujamrus et al., 2018).


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Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Frances E Lock et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(34), E3534-E3543 (2014-08-13)
Remnants of ancient transposable elements (TEs) are abundant in mammalian genomes. These sequences harbor multiple regulatory motifs and hence are capable of influencing expression of host genes. In response to environmental changes, TEs are known to be released from epigenetic
Daniele de Sanctis et al.
The Journal of biological chemistry, 280(29), 27222-27229 (2005-05-27)
Hemoglobins at high concentration have been isolated long ago from some insect larvae living in hypoxic environments. Conversely, a monomeric hemoglobin has been discovered recently in the fruit fly Drosophila melanogaster as intracellular protein expressed both in larvae and in
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Nucleotide-binding domains (NBDs), which are roughly 27 kDa in size, are conserved components of the large family of ABC (ATP-binding cassette) transporters, which includes importers and exporters. NBDs, or ABC-ATPases, supply energy for the translocation of a vast range of
Adrian Sculptoreanu et al.
Experimental neurology, 219(2), 562-573 (2009-07-28)
Neurokinins (NK) released from terminals of dorsal root ganglion (DRG) neurons may control firing of these neurons by an autofeedback mechanism. In this study we used patch clamp recording techniques to determine if NKs alter excitability of rat L4-S3 DRG
S Morgutti et al.
The New phytologist, 171(2), 315-328 (2006-07-27)
The changes in endopolygalacturonase (endo-PG) levels and endo-PG expression in nonmelting flesh (NMF) and melting flesh (MF) peach fruits (Prunus persica) during softening were studied. The endo-PG gene was analysed to identify polymorphisms exploitable for early marker-assisted selection (MAS) of

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