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EMU214511

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting mouse Nav3

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

description

Quality Level

100

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

CAGCCACCGGAAAATATCACTTTTCCAACTTGGTGAGTCCCACCAACCTCTCCCAGTTTAACCTGCCTGCACCCAGTATGATGCGCTCCAGCAGTATCCCCGCCCAGGACTCCTCCTTCGACCTCTATGATGATGCCCAGCTTTGCGGTAGTGCAACTTCCCTGGAGGAAAGGCCACGGGCCGTTAGCCACTCCGGCTCATTCAGAGACAGCATGGAGGAAGTTCATGGCTCTTCACTGTCATTGGTCTCCAGCACATCATCCCTTTACTCTACGGCTGAAGAGAAGGCTCATTCAGAGCAAATCCATAAGCTACGGAGAGAACTGGTTGCCTCCCAGGAGAAAGTCGCTACCCTCACGTCTCAGCTGTCAGCAAATGCTCACCTTGTAGCAGCTTTTGAAAAGAGTTTAGGGAATATGACTGGCCGTTTGCAAAGTCTAACCATGACAGCGGAACAAAAGGAATCTGAGCTTATCGAACTGCGGGAAACCATTGAAATGTTGAAGGCCCAGAA

Ensembl | mouse accession no.

ENSMUSG00000020181

NCBI accession no.

NM_001081035

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... NAV3(260315) , Nav3(260315)

Related Categories

MISSION® esiRNA

General description

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells.

Ryan Charles Pink et al.

Gynecologic oncology, 137(1), 143-151 (2015-01-13)

Ovarian cancer is the deadliest gynaecological cancer. A major contributor to the poor survival rate is the development of chemoresistance to platinum-based therapies such as cisplatin and carboplatin. Here we aimed to test the role of miRNAs in the acquisition

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