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F8509

Sigma-Aldrich

Fumaric acid

BioReagent, suitable for cell culture

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About This Item

Linear Formula:
HOOCCH=CHCOOH
CAS Number:
110-17-8
Molecular Weight:
116.07
Beilstein/REAXYS Number:
605763
EC Number:
203-743-0
MDL number:
MFCD00002700
UNSPSC Code:
12352207
eCl@ss:
39021709
PubChem Substance ID:
24894967
NACRES:
NA.71

vapor pressure

1.7 mmHg ( 165 °C)

product line

BioReagent

assay

≥98%

form

powder

autoignition temp.

1364 °F

expl. lim.

40 %

technique(s)

cell culture | mammalian: suitable

mp

298-300 °C (subl.) (lit.)

SMILES string

OC(=O)\C=C\C(O)=O

InChI

1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+

InChI key

VZCYOOQTPOCHFL-OWOJBTEDSA-N

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Application

A TCA (Krebs cycle) molecule used as a supplement in insect and mammalian cell culture.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

wgk_germany

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fumaric acid United States Pharmacopeia (USP) Reference Standard

USP

1286708

Fumaric acid

Succinic acid BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich

S9512

Succinic acid

di-Sodium fumarate for synthesis

Sigma-Aldrich

8.20584

di-Sodium fumarate

Fumaric acid solution TraceCERT®, 1H-qNMR Standard, 1 mg/g in D2O

Supelco

76201

Fumaric acid solution

Bas J Meussen et al.
Applied microbiology and biotechnology, 94(4), 875-886 (2012-04-25)
Rhizopus oryzae is a filamentous fungus belonging to the Zygomycetes. It is among others known for its ability to produce the sustainable platform chemicals L: -(+)-lactic acid, fumaric acid, and ethanol. During glycolysis, all fermentable carbon sources are metabolized to
Tahar Ghnaya et al.
Chemosphere, 90(4), 1449-1454 (2012-10-03)
The implication of organic acids in Pb translocation was studied in two species varying in shoot lead accumulation, Sesuvium portulacastrum and Brassica juncea. Citric, fumaric, malic and α-cetoglutaric acids were separated and determined by HPLC technique in shoots, roots and
Emine Akar et al.
Carbohydrate polymers, 90(4), 1634-1641 (2012-09-05)
A novel biodegradable sodium carboxymethyl cellulose (NaCMC)-based hydrogel was synthesized by using fumaric acid (FA) as a crosslinking agent at various ratios. Hydrogels (CMCF) were characterized using Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), X-ray
Timothy E L Douglas et al.
Macromolecular bioscience, 12(8), 1077-1089 (2012-06-01)
Alkaline phosphatase (ALP), an enzyme involved in mineralization of bone, is incorporated into three hydrogel biomaterials to induce their mineralization with calcium phosphate (CaP). These are collagen type I, a mussel-protein-inspired adhesive consisting of PEG substituted with catechol groups, cPEG
C Nieboer et al.
Journal of the American Academy of Dermatology, 20(4), 601-608 (1989-04-01)
For the past two decades fumaric acid (FA) therapy has become an increasingly popular treatment in Western Europe for psoriasis. FA therapy originally was developed by Schweckendiek and subsequently standardized by Schäfer. Schäfer's fumaric acid compound therapy (FACT) consists of
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