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G1513

Sigma-Aldrich

Glycerol formal

47-67% 5-hydroxy-1,3-dioxane basis (GC), 33-53% 4-hydroxymethyl-1,3-dioxolane basis (GC)

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About This Item

Empirical Formula (Hill Notation):
C4H8O3
CAS Number:
99569-11-6
Molecular Weight:
104.10
Beilstein/REAXYS Number:
103206
MDL number:
MFCD10039829
UNSPSC Code:
50161901
PubChem Substance ID:
24895065
NACRES:
NA.25

Quality Level

200

contains

~0.02% 2,6-di-tert-butyl-4-methylphenol as stabilizer

composition

5-hydroxy-1,3-dioxane, 47-67% GC
4-hydroxymethyl-1,3-dioxolane, 33-53% GC

refractive index

n20/D 1.451 (lit.)

bp

192-193 °C (lit.)

density

1.203 g/mL at 25 °C (lit.)

SMILES string

OCC1COCO1.OC2COCOC2

InChI

1S/2C4H8O3/c5-4-1-6-3-7-2-4;5-1-4-2-6-3-7-4/h2*4-5H,1-3H2

InChI key

JIUMSISXCKWZTA-UHFFFAOYSA-N

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General description

Glycerol formal (GlyF) includes isomers, namely, 4-hydroxymethyl-1,3-dioxolane and 5-hydroxy-1,3-dioxane. It is a glycerol synthon with a combination of two 5- and 6-membered ring isomers.

Application

Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery. Glycerol formal was used as a vehicle for antibiotic delivery in rats.

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

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