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GE28-9269-81

HiScreen™ Capto™ Adhere

Cytiva 28-9269-81

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About This Item

UNSPSC Code:
23151817
NACRES:
NA.56

ligand

N-benzyl-N-methyl ethanolamine

description

Ion Exchanger Type (value)

packaging

pkg of 1 ea

manufacturer/tradename

Cytiva 28-9269-81

parameter

44 psi

bed size

7.7 mm × 100 mm

bed volume

4.7 mL

column I.D.

7.7 mm

matrix

highly cross-linked agarose

avg. part. size

75 (d₅₀v is the median particle size of the cumulative volume distribution)

cleaning

2-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)

working range

3-12(pH interval where the medium can be operated without significant change in function.)

suitability

suitable for bioprocess medium

Related Categories

General description

HiScreen Capto adhere columns are prepacked with Capto adhere ion exchange chromatography resins, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening. The small column volume of 4.7 mL and bed height of 10 cm make HiScreen columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up.

Features and Benefits

  • Capto adhere is a multimodal anion exchanger for intermediate purification and polishing of monoclonal antibodies after the protein A capture step, giving the possibility to design a two-step chromatographic downstream process.
  • Prepacked, ready-to-use columns for convenient process development optimization.
  • 10 cm bed height of HiScreen columns is designed to allow method optimization and parameter screening.
  • Easily connected in series to achieve 20 cm bed height.
  • Small bed volume gives fast results and minimal sample/buffer consumption.
  • Reproducible results, scalable to BioProcess columns packed with the same resin using the same linear fluid velocity.

Storage and Stability

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Capto is a trademark of Cytiva
HiScreen is a trademark of Cytiva

pictograms

Flame
GHS02

signalword

Warning

hcodes

H226

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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