Skip to Content
MilliporeSigma
All Photos(1)

Documents

J3955

Sigma-Aldrich

JTC-801

≥98% (HPLC)

Synonym(s):

N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C26H25N3O2 · HCl
CAS Number:
244218-51-7
Molecular Weight:
447.96
MDL number:
MFCD06198707
UNSPSC Code:
12352200
PubChem Substance ID:
329815410
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

tan

solubility

DMSO: ≥20 mg/mL

storage temp.

2-8°C

SMILES string

Cl.CCc1ccc(OCc2ccccc2C(=O)Nc3ccc4nc(C)cc(N)c4c3)cc1

InChI

1S/C26H25N3O2.ClH/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25;/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30);1H

InChI key

NQLIYKXNAXKMBL-UHFFFAOYSA-N

Biochem/physiol Actions

JTC-801 is a nociceptin/orphanin FQ peptide (NOP) receptor antagonist.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Keiichi Hiramoto et al.
Photodermatology, photoimmunology & photomedicine, 33(2), 84-91 (2017-01-01)
We previously reported that ultraviolet (UV) A eye irradiation reduces the ulcerative colitis induced by dextran sodium sulfate (DSS). This study examined the effects of UVA on colon carcinoma induced by azoxymethane (AOM) and DSS. We irradiated the eyes of
G Delaney et al.
Journal of neuroendocrinology, 24(12), 1527-1541 (2012-07-28)
Central nociceptin/orphanin FQ (N/OFQ)-expressing neurones are abundantly expressed in the hypothalamus and limbic system and are implicated in the regulation of activity of the hypothalamic-pituitary-adrenal axis (HPA) and stress responses. We investigated the role of the endogenous N/OFQ receptor (NOP)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service