L0665
Lambda Light Chains (Free) from human myeloma sera
purified immunoglobulin, ~1.0 mg/mL, ≥99% (Purity by double diffusion), buffered aqueous solution
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About This Item
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biological source
human
Quality Level
antibody form
purified immunoglobulin
assay
≥99% (Purity by double diffusion)
form
buffered aqueous solution
concentration
~1.0 mg/mL
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Immunoglobulins (Ig) are produced by the B cells and play crucial role in host humoral immune response. A typical immunoglobulin consists of two heavy chains and two light chains. The two light chains are either κ or the λ chain. The B cells express one type of light chain during their life time
λ Light Chains (Free) from human myeloma sera consists of IgG λ light chains purified from myeloma sera.
λ Light Chains (Free) from human myeloma sera consists of IgG λ light chains purified from myeloma sera.
Application
λ Light Chains (Free) from human myeloma sera may be used as immunoglobulin calibrator, blocking agent or coating protein in various immunoassays.
Physical form
Solution in 0.01 M phosphate and 0.15 M sodium chloride, pH 7.2, containing 1.0 M glycine and 0.1% sodium azide.
Preparation Note
Purified from pooled IgG lambda myeloma sera.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Jerry A Katzmann et al.
Clinical chemistry, 48(9), 1437-1444 (2002-08-27)
The detection of monoclonal free light chains (FLCs) is an important diagnostic aid for a variety of monoclonal gammopathies and is especially important in light-chain diseases, such as light-chain myeloma, primary systemic amyloidosis, and light-chain-deposition disease. These diseases are more
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