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L5125

Sigma-Aldrich

N-Lauroylsarcosine sodium salt

≥94%

Synonym(s):

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
Beilstein/REAXYS Number:
5322974
EC Number:
205-281-5
MDL number:
MFCD00042728
UNSPSC Code:
12352107
PubChem Substance ID:
57654330
NACRES:
NA.32

description

anionic

Quality Level

200

assay

≥94%

form

powder

mol wt

micellar avg mol wt 600
average mol wt 600

aggregation number

2

technique(s)

oligo synthesis: suitable

CMC

14.6 mM (20-25°C)

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

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Application

N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay. It has been used for lysing protoplasts in the process of chromosomal DNA isolation form Streptococcus mutans.

Biochem/physiol Actions

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Other Notes

Anionic surfactant.

pictograms

CorrosionSkull and crossbones
GHS05,GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N S Andrade et al.
Genetics and molecular research : GMR, 7(4), 1414-1421 (2009-02-19)
Baccharis dracunculifolia De Candole (DC) (Asteraceae) is indigenous throughout southeastern Latin America and is used by local people in traditional medicine. This plant is known to be the source of resin for the highly valued Brazilian green propolis. As no
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Journal of clinical microbiology, 27(2), 274-278 (1989-02-01)
Attempts to study the acquisition, transmission, and other aspects of the natural history of Streptococcus mutans infections in humans have been hampered by limitations and inconsistencies in methods by which phenotypic characteristics of individual isolates are examined. Because most mutans
M J Stack et al.
Journal of comparative pathology, 116(2), 181-189 (1997-02-01)
Standardized samples of tissue from the central nervous system of four sheep naturally affected with scrapie and from four healthy control sheep were subjected to a centrifugal extraction technique used to obtain scrapie-associated fibrils; the latter were then demonstrated by
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
S Roy et al.
Antimicrobial agents and chemotherapy, 45(6), 1671-1681 (2001-05-17)
The microbicidal efficacies of two anionic surfactants, sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), were evaluated in cultured cells and in a murine model of herpes simplex type 2 (HSV-2) intravaginal infection. In vitro studies showed that SLS and LS
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