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M0443

Sigma-Aldrich

Mirtazapine

≥98% (HPLC)

Synonym(s):

1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine

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About This Item

Empirical Formula (Hill Notation):
C17H19N3
CAS Number:
85650-52-8
Molecular Weight:
265.35
MDL number:
MFCD00865427
UNSPSC Code:
12352200
PubChem Substance ID:
24724531
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: 8 mg/mL, clear

SMILES string

CN1CCN2C(C1)c3ccccc3Cc4cccnc24

InChI

1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3

InChI key

RONZAEMNMFQXRA-UHFFFAOYSA-N

Gene Information

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , DRD2(1813) , DRD3(1814) , DRD4(1815) , HRH1(3269) , HTR1A(3350) , HTR2A(3356) , HTR2C(3358) , HTR7(3363)
mouse ... Slc6a2(20538)
rat ... Adra1a(29412) , Drd1a(24316) , Drd2(24318) , Htr1a(24473) , Htr2a(29595) , Htr2c(25187) , Slc6a3(24898) , Slc6a4(25553)

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Biochem/physiol Actions

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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