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N7287

Sigma-Aldrich

NU-1025

≥97% (HPLC), solid

Synonym(s):

8-Hydroxy-2-methylquinazolin-4[3H]-one

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About This Item

Empirical Formula (Hill Notation):
C9H8N2O2
CAS Number:
90417-38-2
Molecular Weight:
176.17
MDL number:
MFCD00942555
UNSPSC Code:
12352200
PubChem Substance ID:
24724555
NACRES:
NA.77

Quality Level

100

assay

≥97% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble >20 mg/mL
H2O: insoluble

storage temp.

−20°C

SMILES string

CC1=Nc2c(O)cccc2C(=O)N1

InChI

1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)

InChI key

YJDAOHJWLUNFLX-UHFFFAOYSA-N

Gene Information

mouse ... Parp2(11546)

Biochem/physiol Actions

NU-1025 is a PARP inhibitor.

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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The characteristics of the sleep drivers and the mechanisms through which sleep relieves the cellular homeostatic pressure are unclear. In flies, zebrafish, mice, and humans, DNA damage levels increase during wakefulness and decrease during sleep. Here, we show that 6 h
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