Skip to Content
MilliporeSigma
All Photos(1)

Documents

P1742

Sigma-Aldrich

Prealbumin from human plasma

lyophilized powder

Synonym(s):

Thyroxine binding prealbumin, Transthyretin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
87090-18-4
MDL number:
MFCD00132069
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

human plasma

Quality Level

200

assay

≥95% (SDS-PAGE)

form

lyophilized powder

technique(s)

immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable

solubility

H2O: soluble 1 mg/mL

ε (extinction coefficient)

13.5 at 280 nm at 1%

UniProt accession no.

P02766

storage temp.

−20°C

Gene Information

human ... TTR(7276)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver. It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.

Application

Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.
Prealbumin from human plasma has been used as a positive control in immunoprecipitation as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid.

Biochem/physiol Actions

Human prealbumin has been observed in carcinoid tumors.
Prealbumin levels are indictors of malnutrition and may be modulated during inflammation. It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis. Low levels of prealbumin poses high risk to heart failure (HF).

Packaging

Package size based on protein content

Physical form

Lyophilized powder containing sodium phosphate and NaCl

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 8

1 of 8

Albumin, Human Serum, Fraction V, High Purity

Sigma-Aldrich

126658

Albumin, Human Serum, Fraction V, High Purity

Ceruloplasmin human lyophilized powder, oxidase 20-75 units/mg protein

Sigma-Aldrich

C4519

Ceruloplasmin human

Antithrombin III from human plasma lyophilized powder, ≥95% (SDS-PAGE)

Sigma-Aldrich

A2221

Antithrombin III from human plasma

Albumin human Cellastim S™, recombinant, expressed in rice, lyophilized powder, suitable for cell culture, low endotoxin, ≥96% (SDS-PAGE)

Sigma-Aldrich

A9731

Albumin human

Albumin human recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

Sigma-Aldrich

A7736

Albumin human

Sigma-Aldrich

Sigma-Aldrich

H3536

Haptoglobin from pooled human plasma

L-Thyroxine powder, BioReagent, suitable for cell culture

Sigma-Aldrich

T1775

L-Thyroxine

L-Thyroxine ≥98% (HPLC)

Sigma-Aldrich

T2376

L-Thyroxine

Serum albumin and prealbumin in calorically restricted, nondiseased individuals: a systematic review
Lee JL, et al
The American Journal of Medicine, 128(9), 1023-e1-1023-e1 (2015)
K Tashima et al.
Journal of the neurological sciences, 171(1), 19-23 (1999-11-24)
Since 1990, liver transplantation for familial amyloidotic polyneuropathy (FAP) has been carried out world-wide, and the outcome of the procedure seems to be promising. FAP is inherited systemic disease caused by mutated transthyretin. The most common cause is the valine
Gen Sobue
Rinsho shinkeigaku = Clinical neurology, 43(11), 769-774 (2004-05-22)
A nationwide study of CMT and FAP has been performed. In FAP TTR Met30 families with late onset, neuropathy showed male preponderance, low penetrance, little relationship to endemic foci, sensorimotor symptoms beginning distally in the lower extremities with disturbance of
J Figueras et al.
Medicina clinica, 116(10), 377-379 (2001-05-03)
Domino or sequential liver transplantation (DTXL) is a kind of living donor transplant, which was proposed in 1993 and performed for the first time in 1995; later on, more than 45 have been reported. The liver from a patient with
David Adams et al.
Presse medicale (Paris, France : 1983), 41(9 Pt 1), 793-806 (2012-02-22)
The treatment of familial amyloid polyneuropathies (FAP) is complex and requires a neurological and cardiological multidisciplinary coverage. It includes specific treatments to control the progression of the systemic amyloidogenesis, the symptomatic treatment of the peripheral and autonomic neuropathy (digestive, urinary
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service