P1922
Monoclonal Anti-Progesterone antibody produced in rat
clone 2H4, tissue culture supernatant
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About This Item
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biological source
rat
Quality Level
conjugate
unconjugated
antibody form
tissue culture supernatant
antibody product type
primary antibodies
clone
2H4, monoclonal
technique(s)
indirect ELISA: 1:1000 - 1:2000 (using Progesterone-BSA for coating.)
radioimmunoassay: suitable
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Progesterone or P4 (pregn-4-ene-3,20-dione) is a female steroid hormone that belongs to the hormones class, progestogens. It is produced by majorly by ovaries, adrenal glands and placenta of humans and other species. Progesterone derived from placenta and corpus luteum is required for the maintenance of pregnancy. Progesterone inhibits the T cell mediated immune response involved in tissue rejection. The progesterone levels in females are low before ovulation and are elevated during the luteal phase. Monoclonal Anti-Progesterone antibody is IgG1 isotype purified from rat cell culture supernatant.
Immunogen
progesterone-7-BSA.
Application
The antibody may be used in various immunochemical techniques including ELISA, radioimmunoassay AND RIA to measure progesterone levels in milk.
Analysis Note
dextran coated charcoal 3H RIA.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Journal of dairy science, 100(10), 8205-8219 (2017-08-15)
The objectives of this study were (1) to analyze the agreement of a standard laboratory ELISA for progesterone (P4) with an automated on-farm ELISA kit operated under commercial conditions in 1,297 milk samples from 50 dairy cows; (2) to study
The Journal of reproduction and development, 57(1), 43-48 (2010-10-19)
The objective of this study was to investigate the relationships between uterine perfusion and estrogen, progesterone and the uterine nitric oxide synthase (NOS) system in five trotter mares during the estrous cycle. Color Doppler sonography for measurement of uterine blood
Steroids, 67(7), 565-572 (2002-05-09)
A series of progesterone-4-ovalbumin (OVA) conjugates with different length linkers (4-, 11-, and 18-atoms long) were synthesized by successive aminocaproic acid homologation of 3-(pregn-4-ene-3,20-dione-4-yl)thiopropanoic acid (1) before conjugation to ovalbumin. The performance studies of these progesterone-4-ovalbumin conjugates showed that the
Theriogenology, 71(5), 754-761 (2008-11-18)
Diagnosis of pregnancies is an important management tool for the Iberian lynx Conservation Breeding Program, a program geared to recover the world's most endangered felid. Non-invasive methods such as fecal hormone analyses are not applicable to the lynx, since fecal
Reproduction (Cambridge, England), 144(4), 477-484 (2012-07-26)
Lynx presents a unique sexual cycle with persistent corpora lutea (CLs) and elevated serum progesterone (P₄) throughout parturition and lactation. In other mammals, CLs normally disintegrate after parturition, therefore the aim of our study was to characterise the annual life
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