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P2008

Sigma-Aldrich

Polyanetholesulfonic acid sodium salt

powder

Synonym(s):

Sodium polyanetholesulfonate

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About This Item

CAS Number:
55963-78-5
MDL number:
MFCD00148427
UNSPSC Code:
12162002
NACRES:
NA.77

form

powder

Quality Level

200

storage condition

(Tightly closed. Dry.)

color

yellow

solubility

water: 1 g/10 mL, clear to hazy, yellow to very dark yellow-orange

SMILES string

C/C=C/C1=CC=C(C=C1)OC.[O-]S(=O)[O-].[Na+]

InChI

1S/C10H12O.Na.H2O3S/c1-3-4-9-5-7-10(11-2)8-6-9;;1-4(2)3/h3-8H,1-2H3;;(H2,1,2,3)/q;+1;/p-2/b4-3+;;

InChI key

JKJBFNAERWARKW-CZEFNJPISA-L

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General description

Canonical SMILES: CC=CC1=CC=C(C=C1)OC.[O-]S(=O)[O-].[Na+]

Application

Polyanetholesulfonic acid sodium salt:
  • has been used as a component in BACTEC plus aerobic/F medium or blood culture media to decrease the barrier for bacterial growth
  • has been used to inhibit the activity of classical pathway (CP) and alternative pathway (AP)
  • may be used in the preparation of bifunctional/polymeric composite gel beads to remove cationic dyes

Biochem/physiol Actions

Polyanetholesulfonic acid sodium salt is a polymeric phosphor. It can recognize ferric ion (Fe3+) effectively. Sodium polyanethole sulfonate (SPS) is used in commercial blood culture bottles as an anticoagulant. It can prevent the humoral and cellular elements that might interfere with the growth of bacteria. SPS may influence the complement system. It can block phagocytosis and leukocyte functions.

Other Notes

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pictograms

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GHS07

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ying Pei et al.
Antiviral research, 89(1), 98-108 (2010-11-27)
To investigate the anti-herpesvirus mechanism of pentagalloylglucose (PGG), we compared the proteomic changes between herpes simplex virus type 1 (HSV-1) infected MRC-5 cells with or without PGG-treatment, and between non-infected MRC-5 cells with or without PGG-treatment by 2-DE and MS-based
Ying Pei et al.
Biochemical and biophysical research communications, 405(2), 186-191 (2011-01-11)
Pentagalloylglucose (PGG) is a natural polyphenolic compound with broad-spectrum anti-viral activity, however, the mechanisms underlying anti-viral activity remain undefined. In this study, we investigated the effects of PGG on anti-viral activity against Herpes simplex virus type 1 (HSV-1) associated with
Effect of polyanetholesulphonic acid and xylan sulphate on antithrombin III activity.
G Kindness et al.
Biochemical and biophysical research communications, 88(3), 1062-1068 (1979-06-13)
P C Braga et al.
Experimental gerontology, 33(5), 477-484 (1998-10-08)
Phagocytic defensive functions consist of a sequence of events, including migration, phagocytosis, secretion, and the release of reactive oxygen species (ROS). The last of these (also called "oxidative burst") has not received due attention in the elderly, even though it
I Ginsburg et al.
Free radical biology & medicine, 7(4), 369-376 (1989-01-01)
Previous studies have demonstrated that a number of membrane-active agents are capable of binding to the surface of polymorphonuclear leukocytes (PMN) resulting in an augmentation of superoxide anion and hydrogen peroxide (H2O2) production in response to soluble stimuli. It is
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