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PLA0160

Sigma-Aldrich

Rabbit anti-CBX3 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

HECH, HP1 gamma, HP1 gamma homolog, HP1 gamma homolog (Drosophila), HP1-GAMMA, HP1Hs-gamma, chromobox homolog 3, chromobox homolog 3 (Drosophila HP1 gamma), chromobox homolog 3 (HP1 gamma homolog; Drosophila), heterochromatin protein 1 homolog gamma, heterochromatin protein HP1 gamma, heterochromatin-like protein 1, modifier 2 protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

immunohistochemistry: 1:2,000-1:10,000
immunoprecipitation (IP): 2-5 μg/mg

accession no.

NP_009207.2

UniProt accession no.

Q13185

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... CBX3(11335)

Immunogen

The epitope recognized by PLA0160 maps to a region between residue 133 and the C-terminus (residue 183) of human chromobox homolog 3 using the numbering given in entry NP_009207.2 (GeneID 11335).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

CBX3 (chromobox protein homolog 3), also known as HP1gamma (heterochromatin protein 1 homolog gamma), is one of 3 isoforms of HP1 that binds heterochromatin and functions as a structural adaptor to stabilize and organize macromolecular complexes with nucleosomes for higher chromatin structure. All of the HP1 isoforms possess a chromodomain and chromoshadow domain and associate with methylated histones that mediate transcriptional repression.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Certificates of Analysis (COA)

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