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PLA0262

Sigma-Aldrich

Rabbit anti-Dcp2 Antibody, Affinity Purified

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Synonym(s):

DCP2 decapping enzyme homolog, DCP2 decapping enzyme homolog (S. cerevisiae), M(7)GpppN-mRNA hydrolase, NUDT20, Nucleoside diphosphate-linked moiety X motif 20, Nudix motif 20, hDpc, mRNA-decapping enzyme 2, nudix (nucleoside diphosphate linked moiety X)-type motif 20

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

immunoprecipitation (IP): 5-15 μg/mg
western blot: 1:1,000-1:5,000

accession no.

NP_689837.2

UniProt accession no.

Q8IU60

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... Dcp2(167227)

Immunogen

The epitope recognized by PLA0262 maps to a region between residue 370 and 420 of human mRNA-decapping enzyme 2 using the numbering given in entry NP_689837.2 (GeneID 167227).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

mRNA-decapping enzyme 2 (Dcp2) is required for both normal mRNA turnover and nonsense-mediated mRNA decay. Dcp2 plays a role in replication-dependent histone mRNA degradation. It removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5′-phosphorylated mRNA fragment and 7m-GDP [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IU60].

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Certificates of Analysis (COA)

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