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RAB0260

Sigma-Aldrich

Mouse IL-15 ELISA Kit

for serum, plasma and cell culture supernatant

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 500 pg/mL
standard curve range: 0.33-80 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Il15(16168)

Related Categories

General description

The Mouse IL-15 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-15 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Mouse IL-15

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin 15 (IL-15) is a proinflammatory cytokine, expressed in monocytes and macrophages. IL-15 promotes T cell proliferation and adhesion to endothelial cells along with cluster of differentiation (CD44). IL-15 is a chemoattractant of natural killer (NK) cells and promotes its growth. IL-15 is associated with inflammatory disease like rheumatoid arthritis. Hypercholesteremia upregulates the expression of IL-15. Overexpression of IL-15 is implicated in cardiovascular disease and atherosclerosis. Polymorphism in IL-15 might cause celiac disease, a chronic autoimmune disease condition. The concentration of IL-15 in follicular fluid is inversely proportional to the size of the follicles and thus, affects the maturity of the oocytes. Polymorphism in IL-15 is associated with hepatocellular carcinoma.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABELADDELISA 5X Assay/Sample Diluent Buffer D (Item K)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Interleukin 15 concentrations in follicular fluid and their effect on oocyte maturation in subfertile women undergoing intracytoplasmic sperm injection
Spanou S, et al.
Journal of Assisted Reproduction and Genetics, 35(6), 1019-1025 (2018)
Association between Recipient IL-15 Genetic Variant and the Prognosis of HBV-Related Hepatocellular Carcinoma after Liver Transplantation
Zhang T, et al.
Disease Markers, 2017 (2017)
IL-15 aggravates atherosclerotic lesion development in LDL receptor deficient mice
van Es T, et al.
Vaccine, 29(5), 976-983 (2011)
Association of the IL-15 and IL-15R alpha genes with celiac disease
Escudero-Hernandez C, et al.
Cytokine, 99, 73-79 (2017)
IL-15 polymorphisms are associated with subclinical atherosclerosis and cardiovascular risk factors. The Genetics of Atherosclerosis Disease (GEA) Mexican Study
Angeles-Martinez J, et al.
Cytokine, 99, 173-178 (2017)
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