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RAB0687

Sigma-Aldrich

Human IL1F7 / Interleukin-37 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 81.92-20000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL1F7(27178)

Related Categories

General description

The IL1F7 ELISA kit provides for the quantitative measurement of IL-37 in cell culture supernatants, plasma and serum.
The interleukin 37 (IL1F7) gene is expressed in several tissues such as thymus, lymph nodes, testis, uterus, placenta, bone marrow and lungs. The gene IL1F7 exists in five isoforms IL1F7a-e. The IL1F7 gene is mapped to human chromosome 2q14.1.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin 37 (IL1F7) suppresses the innate immune response. The IL1F7 gene expression is associated with many inflammatory disorders including dermatosis, hepatopathy, digestive system disorders, autoimmune diseases, ischemia/reperfusion injury and other metabolic diseases. The anti-inflammatory action of IL1F7 might affect tumor inflammation mechanism.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Associations of the Interleukin?1 Gene Locus Polymorphisms with Risk to Hip and Knee Osteoarthritis: Gender and Subpopulation Differences.
Kaarvatn M H, et al.
Human immunology, 77(2), 151-161 (2013)
Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma.
Lin L, et al.
Scientific Reports, 6, 26757-26757 (2016)
Javier Rodríguez-Carrio et al.
Frontiers in immunology, 9, 2351-2351 (2018-10-30)
Introduction: B-cell activation is pivotal in rheumatoid arthritis (RA) pathogenesis and represents a relevant therapeutic target. The main aim of this study was to characterize the profiles of B-cell factors and their decoy receptors in RA and evaluate their clinical
The effects of selective hematopoietic expression of human IL-37 on systemic inflammation and atherosclerosis in LDLr-deficient mice.
Hoeke G, et al.
International Journal of Molecular Sciences, 18(8), 1672-1672 (2017)

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