Skip to Content
MilliporeSigma
All Photos(3)

Documents

S006

Sigma-Aldrich

Ketanserin (+)-tartrate salt

≥97%, solid

Synonym(s):

3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt, R 41468 (+)-tartrate salt

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C22H22FN3O3 · C4H6O6
CAS Number:
Molecular Weight:
545.51
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥97%

form

solid

color

white

solubility

ethanol: 3 mg/mL
DMSO: 52 mg/mL (lit.)(lit.)
0.1 M HCl: 6 mg/mL (lit.)(lit.)

storage temp.

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O

InChI

1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key

KMTLTEVOQLMYRS-LREBCSMRSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

Application

Ketanserin (+)-tartrate salt has been used:
  • as a 5HT2A antagonist in Krebs-Henseleit buffer solution
  • for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior
  • to study the behavioural changes of incision pain rats

Biochem/physiol Actions

Ketanserin stimulates collagen synthesis and is involved in wound healing.
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 6

1 of 6

Pindolol ≥98% (TLC), powder

Sigma-Aldrich

P0778

Pindolol

Piracetam

Sigma-Aldrich

P5295

Piracetam

Effects of short-term exposure to ectoparasites on fish cortisol and hematocrit levels
Triki Z, et al.
Marine biology, 163(9), 187-187 (2016)
The 5-HT2A receptor potassium-chloride cotransporter 2 signaling pathway in a rat incision pain model
Dong R, et al.
Experimental and Therapeutic Medicine, 12(6), 3583-3588 (2016)
Ketanserin in wound healing and fibrosis: investigations into its mechanism of action
Serotonin, 12(6), 451-455 (1990)
Iris Lim et al.
European journal of pharmacology, 818, 328-334 (2017-11-07)
Isolated ureteral strips develop spontaneous phasic contractile activity which is enhanced by 5-hydroytryptamine (5-HT). The aim of this study was to identify the receptor subtype mediating these responses and to determine whether responses to 5-HT change with age. The frequency
Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue
Klotz JL, et al.
Journal of Animal Science, 91(9), 4492-4500 (2013)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service