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SAB1406089

Sigma-Aldrich

Anti-LOR antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

MGC111513

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~26 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

BC034690.1

UniProt accession no.

P23490

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LOR(4014)

General description

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel′s syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. (provided by RefSeq)

Immunogen

LOR (AAH34690.1, 1 a.a. ~ 316 a.a) full-length human protein.

Sequence
MSYQKKQPTPQPPVDCVKTSGGGGGGGGGGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK

Physical form

Solution in phosphate buffered saline, pH 7.4

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Kyung Ah Cheong et al.
Journal of dermatological science, 76(2), 112-119 (2014-09-23)
Hydroquinone (HQ) with or without retinoic acid (RA) is routinely used for the treatment of hyperpigmented conditions. Skin irritation is a major problem with popular depigmenting agents, resulting in postinflammatory hyperpigmentation. To examine the molecular mechanism associated with skin irritation

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