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SAB2106753

Sigma-Aldrich

Anti-GOLIM4 antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

75 kDa

species reactivity

dog, rabbit, mouse, human, horse, rat, bovine, guinea pig

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NM_001191567

UniProt accession no.

O00461

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GOLIM4(27333)
rat ... Golim4(310526)

General description

Golgi internal membrane protein 4 (GOLIM4) is a golgi type II transmembrane phosphoprotein. In human chromosome, the gene GOLIM4 is located on 3q26.2.

Immunogen

The immunogen for anti-GOLIM4 antibody: synthetic peptide derected towards the C terminal of human GOLIM4

Biochem/physiol Actions

Golim4 plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi. Golim4 plays a major role in maintaining manganese homeostasis. The expression level of Golim4 is less in cancer cells. GOLIM4 is a potential oncogene, regulates cell cycle and apoptosis in neck and cancer cells.

Sequence

Synthetic peptide located within the following region: DPGNRQEFHEPGHQEGDPEAEADRAAAQDINPADDPNNQGEDEFEEAEQV

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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