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SAB3501142

Sigma-Aldrich

Anti-SARS-CoV-2 (COVID-19) NSP13 (Helicase) antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

SARS coronavirus

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG

NCBI accession no.

YP_009725308.1

UniProt accession no.

P0DTC1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

SARS coronavirus ... ORF1ab(43740578)

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General description

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP13 is a multi-functional protein with a zinc-binding domain in N-terminus displaying RNA and DNA duplex-unwinding activities with 5′ to 3′ polarity. Activity of Helicase is dependent on magnesium(3,4).

Immunogen

Anti-SARS-CoV-2 (COVID-19) NSP13 (Helicase) antibody was raised against a peptide corresponding to 19 amino acids near the carboxyl terminus of the SARS-CoV-2 (COVID-19) NSP13 (Helicase) protein. The immunogen is located in the last 50 amino acids of SARS-CoV-2 (COVID-19) NSP13 (Helicase).

Application

Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP13 antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 NSP13 recombinant protein by ELISA. All other applications and species not yet tested

Physical form

Supplied in PBS containing 0.02% sodium azide.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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