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SAB3501226

Sigma-Aldrich

Anti-TRBP1 antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human, mouse

concentration

1 mg/mL

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TARBP1(6894)

General description

TRBP1 Antibody: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1α (EF-1α), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

Immunogen

TRBP1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1.The immunogen is located within amino acids 1310 - 1360 of TRBP1.

Application

TRBP1 antibody can be used for detection of TRBP1 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Physical form

Supplied in PBS containing 0.02% sodium azide.

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Certificates of Analysis (COA)

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