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SAB3501278

Sigma-Aldrich

Anti-Puumala Virus Nucleocapsid antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

virus (Puumala virus)

concentration

1 mg/mL

technique(s)

ELISA: suitable

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

Puumala virus ... PUUVsSgp1(2943083)

General description

Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus. Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc). These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle.

Immunogen

Puumala virus nucleocapsid antibody was raised against a 19 amino acid peptide near the amino terminus of the Puumala virus nucleocapsid.The immunogen is located within amino acids 130 - 180 of Puumala Virus Nucleocapsid.

Application

Puumala virus nucleocapsid antibody can detect 10ng Puumala virus nucleocapsid peptide in ELISA at 1 μg/ml.

Physical form

Supplied in PBS containing 0.02% sodium azide.

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