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SAB4300038

Sigma-Aldrich

Anti-phospho-STAT6 (pTyr641) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-D12S1644 antibody produced in rabbit, Anti-IL-4-STAT antibody produced in rabbit, Anti-STAT6B antibody produced in rabbit, Anti-STAT6C antibody produced in rabbit, Anti-signal transducer and activator of transcription 6, interleukin-4 induced antibody produced in rabbit

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About This Item

MDL number:
MFCD02097176
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~110 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(R-G-YP-V-P)

NCBI accession no.

NP_003144.3

UniProt accession no.

P42226

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr641)

Gene Information

human ... STAT6(6778)

Immunogen

Peptide sequence around phosphorylation site of tyrosine 641 (R-G-Y(p)-V-P), according to the protein STAT6.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Katherine T Venmar et al.
Cancer research, 74(16), 4329-4340 (2014-06-21)
IL4, a cytokine produced mainly by immune cells, may promote the growth of epithelial tumors by mediating increased proliferation and survival. Here, we show that the type II IL4 receptor (IL4R) is expressed and activated in human breast cancer and
E Yaneth Osorio et al.
PLoS pathogens, 10(6), e1004165-e1004165 (2014-06-27)
Host arginase 1 (arg1) expression is a significant contributor to the pathogenesis of progressive visceral leishmaniasis (VL), a neglected tropical disease caused by the intracellular protozoan Leishmania donovani. Previously we found that parasite-induced arg1 expression in macrophages was dependent on
Sun Hee Jin et al.
Toxicology and applied pharmacology, 280(2), 199-206 (2014-08-30)
Keratinocytes are the major cellular components of human epidermis and play a key role in the modulating cutaneous inflammation and toxic responses. In human chronic skin diseases, the common skin inflammatory phenotypes like skin barrier disruption and epidermal hyperplasia are

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