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SAB4300617

Sigma-Aldrich

Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-AI604853 antibody produced in rabbit, Anti-Cdc25b antibody produced in rabbit, Anti-cell division cycle 25 homolog B (S. pombe) antibody produced in rabbit

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About This Item

MDL number:
MFCD01633249
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~62 kDa

species reactivity

mouse

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(F-R-SP-L-P)

NCBI accession no.

NP_001104545.1

UniProt accession no.

P30306

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer149)

Gene Information

mouse ... Cdc25b(12531)

Related Categories

Immunogen

Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P).according to the protein Cdc25b.

Features and Benefits

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Target description

Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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