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SAB4700578

Sigma-Aldrich

Monoclonal Anti-CD11a antibody produced in rat

clone M17/4, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Itgal, Anti-LFA-1 α chain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rat

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

M17/4, monoclonal

form

buffered aqueous solution

species reactivity

mouse

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG2a

NCBI accession no.

NM_008400.2

UniProt accession no.

P24063

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

mouse ... Itgal(16408)

Related Categories

General description

The rat monoclonal antibody M17/4 reacts with CD11a (alpha-subunit of murine LFA-1), a 180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils.

Immunogen

C57BL/6 mouse splenic secondary cytotoxic T lymphocytes

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Rosemary E Smith et al.
Blood, 102(7), 2532-2540 (2003-06-14)
MyD-1 (CD172) is a member of the family of signal regulatory phosphatase (SIRP) binding proteins, which is expressed on human CD14+ monocytes and dendritic cells. We now show a novel role for MyD-1 in the regulation of the innate immune

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