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SAB5200019

Sigma-Aldrich

Monoclonal Anti-DUX4 antibody produced in mouse

clone P2B1, 1 mg/mL, purified immunoglobulin

Synonym(s):

Anti-DUX10, Anti-DUX4, P2B1, Anti-double homeobox 4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

P2B1, monoclonal

form

buffered aqueous glycerol solution

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry: suitable
indirect immunofluorescence: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NP_149418.3

UniProt accession no.

Q9UBX2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DUX4(22947)

General description

DUX4 (double homeobox 4) has been mapped to human chromosome 4q35.2. DUX4 is an open reading frame of tandem array D4Z4. It consists of two homeobox sequences.

Specificity

This antibody recognizes human DUX4. Does not cross react with DUX4c.

Immunogen

C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (GST) tag

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.
Beckers M C, et al.
Gene, 264(1), 51-57 (2001)
Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.
Clapp J, et al.
American Journal of Human Genetics, 81(2), 264-279 (2017)

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