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SAB5200073

Sigma-Aldrich

Monoclonal Anti-KCNIP3 antibody produced in mouse

clone S66-38, 1 mg/mL, purified immunoglobulin

Synonym(s):

Anti-Csen, Anti-Dream, Anti-KChlP3 K+ channel, S66-38, Anti-Kcnip3, Anti-rKChIP3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

S66-38, monoclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 34 kDa

species reactivity

mouse, human, rat

concentration

1 mg/mL

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

NP_115851.1

UniProt accession no.

Q9Y2W7

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Kcnip3(65199)

General description

Potassium voltage-gated channel interacting protein 3 (KCNIP3) is part of the neuronal calcium sensor protein family. The gene ID of the protein is 65199.

Specificity

Detects ~34 kDa. No cross reactivity against KCIPs 1,2 or 4

Immunogen

Fusion protein amino acids 1-256 (Full lenght) of rat Calsenillin/DREAM/KChIP3

Biochem/physiol Actions

Potassium voltage-gated channel interacting protein 3 (KCNIP3) is involved in the downregulation of other genes. It has been shown that the protein is upregulated when there is a high concentration of glucose in vitro.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Rosfaiizah Siran et al.
Journal of physiology and biochemistry, 70(4), 877-889 (2014-09-15)
REM sleep is a crucial component of sleep. Animal studies indicate that rapid eye movement (REM) sleep deprivation elicits changes in gene expression. Down regulatory antagonist modulator (DREAM) is a protein which downregulates other gene transcriptions by binding to the
Erika Chavira-Suárez et al.
Biochemical and biophysical research communications, 418(2), 420-425 (2012-01-27)
Hyperglycemia alters the tight control of intracellular calcium dynamics in retinal cells and may lead to the development of diabetic retinopathy. The potassium channel interacting protein 3 (KChIP3) also known as DREAM (Downstream Regulatory Element Antagonist Modulator) or calsenilin (KChIP3/DREAM/calsenilin)

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