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SAB5700330

Sigma-Aldrich

Anti-Phospho-STAT1-S727 antibody produced in rabbit

Synonym(s):

CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT1, STAT1 alpha, STAT91

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

83
 87

species reactivity

mouse, human, rat

concentration

1.31 mg/ml

technique(s)

immunohistochemistry: 1:50-1:100
immunoprecipitation (IP): 1:50-1:100
western blot: 1:500-1:2000

UniProt accession no.

P42224

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer727)

Gene Information

human ... STAT1(6772)

General description

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Immunogen

A synthetic phosphorylated peptide around S727 of human STAT1 (NP_009330.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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