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SAB5700784

Sigma-Aldrich

Anti-Occludin antibody produced in rabbit

Synonym(s):

BLCPMG, OCLN, Occludin, PPP1R115, PTORCH1, occludin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

23
 31
 52
 54
 59
 8

species reactivity

human, mouse, rat

concentration

1.77 mg/ml

technique(s)

immunofluorescence: 1:50-1:100
immunohistochemistry: 1:50-1:200
western blot: 1:1000-1:2000

UniProt accession no.

Q16625

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... OCLN(100506658)

General description

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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