SAB5701390
Anti- β-Catenin antibody produced in mouse
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About This Item
UNSPSC Code:
12352203
Recommended Products
biological source
mouse
Quality Level
antibody product type
primary antibodies
clone
monoclonal
form
liquid
species reactivity
rat, human, mouse
concentration
1.51 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CTNNB1(1499)
General description
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Immunogen
Recombinant protein of human β-Catenin.
Physical form
Buffer: PBS with 0.05% sodium azide,0.2% BSA,40% glycerol,pH7.4.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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