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SAB5701768

Sigma-Aldrich

Anti-Phospho-SRC Family-Y416 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human

concentration

0.68 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

P12931

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr416)

General description

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding Y416 of human SRC Family

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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