SAB5701957
Anti-Phospho-CGAS-S420 antibody produced in rabbit
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
mouse, human, rat
concentration
0.755 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer420)
Gene Information
mouse ... CGAS(214763)
General description
The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Immunogen
A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS.
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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