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SMB01080

Sigma-Aldrich

Semilicoisoflavone B

≥85% (LC/MS-ELSD)

Synonym(s):

5,7,8′-Trihydroxy-2′,2′-dimethyl-2′H-(3,6′)bi(1-benzopyranyl)-4-one

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About This Item

Empirical Formula (Hill Notation):
C20H16O6
CAS Number:
129280-33-7
Molecular Weight:
352.34
MDL number:
MFCD28100710
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

assay

≥85% (LC/MS-ELSD)

form

solid

mol wt

352.34

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C20H16O6/c1-20(2)4-3-10-5-11(6-15(23)19(10)26-20)13-9-25-16-8-12(21)7-14(22)17(16)18(13)24/h3-9,21-23H,1-2H3

InChI key

LWZACZCRAUQSLH-UHFFFAOYSA-N

Related Categories

General description

Semilicoisoflavone B, is an isoflavonoid belongs to the class of 7-hydroxyisoflavones, is a natural product commonly available from Glycyrrhiza Sp., Mitracarpus scaber, and Lentinus tigrinus. This plant metabolite exhibits various biological activities, including anti-inflammatory, antioxidant, anti-tumor, antiviral, and anti-allergic effects.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Semilicoisoflavone B:
  • Suppresses proinflammatory cytokine production, downregulates TLR4 expression, and diminishes reactive oxygen species generation in vitro.
  • Inhibits the growth and division of cancer cells by triggering apoptosis and arresting the cell cycle, offering potential for effective tumor therapy.
  • Restricts Caco-2 cell proliferation, suggesting potential for metabolic syndrome therapy.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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